Syphilis: Its Early History and Eventual Cure

Mankind was wrecked by the sudden appearance of syphilis in the late 1490s. At its onset and for centuries later, this new disease caused widespread epidemics throughout Western Europe and would eventually threaten nearly the entire world’s population at one time or another. Syphilis is a sexually transmitted infection caused by the bacteria Treponema pallidum, which is a corkscrew-shaped spirochete (a phylum or category of double-membrane bacteria). The exact cause of syphilis, Spirochaeta pallida, was co-discovered in 1905 by German zoologist Fritz Richard Schaudinn and German dermatologist Erich Hoffmann while the pair were working at the Berlin Charité, a large teaching hospital. When syphilis first appeared in the 15th century, its symptoms were much more severe than those of present-day syphilis. The early symptoms included genital ulcers followed by fever, general rash and joint and muscle pains. Weeks or months later, symptoms included large, painful and foul-smelling abscesses and sores, or pocks, all over the body. These sores would become ulcers that could eat into bone and into the lips, nose and eyes as well. Sometimes sores would appear in the mouth or throat and death would occur. People afflicted with the disease suffered from extreme bone pain, especially at night. Immunity to disease occurs after exposure to the disease, whether it be from exposure to the disease itself or to dead or weakened disease cells found within vaccines. Because the 15th century population had yet to develop immunity to syphilis, the disease spread quickly and had a much higher and quicker rate of morbidity than its present-day version. There are two theories as to how syphilis came into...